Hormone Therapy for Transgender and Gender Diverse Adults in Portland, Oregon and Beyond: What to Expect
Gender-affirming care, including hormone therapy, is a vital component of health and well-being for many transgender and gender diverse adults. This care looks different for everyone—it may mean starting testosterone or estrogen, adjusting existing therapy, or simply having a safe space to discuss gender and health. A growing body of research shows that gender-affirming care improves mental health, reduces suicidality, and enhances overall quality of life. Leading medical organizations—including the American Medical Association, American Academy of Family Physicians, Endocrine Society, American Psychiatric Association, and World Professional Association for Transgender Health—affirm the importance of access to gender-affirming treatment as evidence-based, medically necessary care. At PridePoint Health, we provide inclusive, expert-led hormone therapy grounded in this evidence. Whether you’re just beginning or continuing your journey, this guide explains what to expect.
We Provide Gender Affirming Care Throughout Oregon and Washington.
How Does Gender-Affirming Hormone Therapy Work?
Hormone therapy involves testosterone or estrogen-based treatments to support gender expression that aligns with your identity. The specific medications and dosages are tailored to each individual’s goals and medical needs.
Masculinizing Hormone Therapy (for those seeking more masculine characteristics) typically includes testosterone. This can lead to voice deepening, increased muscle mass, body hair growth, and stopping the menstrual cycle.
See our table of masculinizing changes with expected timeline for onset and completion of changes.
Feminizing Hormone Therapy (for those seeking more feminine characteristics) typically includes estradiol and an androgen blocker. Changes may include breast development, skin softening, body fat redistribution, and reduced facial/body hair growth.
See a full list of feminizing changes with expected timeline for onset and completion of changes.
Who is Eligible for Hormone Therapy?
At PridePoint Health, we follow an informed consent model, meaning you do not need a letter from a mental health provider to start hormone therapy. Instead, we provide comprehensive education on the risks, benefits, and expected changes to ensure you can make an informed decision.
Eligibility typically includes:
Being 18 years or older
Having the capacity to provide informed consent
No medical contraindications that would make hormone therapy unsafe
Where We Provide Care
PridePoint Health proudly serves transgender and gender diverse adults across Oregon and Washington, including both urban and rural communities. Whether you're in Portland, Eugene, Bend, Salem, Corvallis, Vancouver, Tacoma, Spokane, or a more remote location, our telehealth and in-person care options ensure you can access affirming, expert-led hormone therapy no matter where you are.
See the full list of cities we serve: Oregon | Washington
Note: These lists are not exhaustive—we provide care to anyone in Oregon or Washington, regardless of specific location.
What’s Included in Your Membership?
Our Gender-Affirming Care Membership is designed to provide comprehensive, high-quality support for patients at every stage of their journey. For $79 per month (active hormone management), your membership includes:
A comprehensive gender-affirming care consultation to assess your medical history, goals, and needs
Personalized hormone management, including initiation, ongoing prescription adjustments, and monitoring to optimize therapy
Coordination and interpretation of laboratory monitoring to track progress and ensure treatment safety
Expert management of hormone-related concerns and side effects, reducing the need for specialist referrals
Access to our private, welcoming clinic space for in-person visits, consultations, and lab testing* as needed
Telemedicine services, offering convenient, secure virtual visits for patients across Oregon and Washington
Prescriptions sent to a mail-order pharmacy or local brick-and-mortar pharmacy
Lab orders sent to a location near you, with mobile phlebotomy options for at-home blood draws
Injection teaching and support, ensuring confidence in self-administering injections
Optional in-clinic hormone injections, available upon request
Pre-surgical evaluations and referrals to gender-affirming surgeons
Referrals for gender-affirming procedures, including laser hair removal, electrolysis, and body contouring
Referrals for voice coaching, to help align vocal presentation with gender identity
Prescription costs and lab work are not included in membership. See below for cost estimates as of 3/2025.
How Much Does Hormone Therapy Cost?
Unlike traditional insurance-based clinics, PridePoint Health offers transparent, affordable pricing through our direct primary care model. This means you get unrestricted access to care without dealing with insurance hurdles. Our membership includes visits, ongoing monitoring, and support for your gender-affirming care.
Prescription Costs (cash price, without insurance)
Prescription cost estimates are for those paying cash price and are based on GoodRx and CostPlusDrugs pricing (as of 3/2025). Your price may vary. Patients of course, can use their insurance for prescriptions. Those costs will depend on the individual policy.
Masculinizing Hormone Therapy:
Androgel (1.62%): $42.03 per 88g (60 pumps) → ~$20/month per pump
Most patients use 2-4 pumps per day → Estimated monthly cost: $40-$80
Testosterone Cypionate (200mg/mL, 1mL vials x4): $53 for 4 vials ($13.25 per 1mL vial)
~$3.31 per 50mg injection (0.25mL) → Estimated monthly cost:
$26-$42 per month for 50-80mg per week dosing (0.25-0.4mL per week)
Feminizing Hormone Therapy:
Estradiol (2mg tablets x 90): $13 → ~$0.14 per tablet
Most patients take 2-3 tablets per day → Estimated monthly cost: $8-$13
Estradiol Valerate (5mL of 20mg/mL): $48-52
Most patients use 0.2mL per week → Estimated monthly cost: $8-$10
Estradiol Patches (0.1mg, 8 patches for twice-weekly use, 6 cartons = $188): $32 per month per patch
Most patients use 2-3 patches per month → Estimated monthly cost: $32-$64
Spironolactone (50-100 mg x 90): $13-20
Most patients take 1 tablet per day → Estimated monthly cost: $5-$7
Lab Costs (our negotiated wholesale cash rates)
PridePoint Health offers wholesale, negotiated lab pricing with up to 90% savings compared to standard retail costs. Patients may also use their insurance for lab testing, but our pricing is often lower than the copay for even premium insurance plans.
Labs are typically drawn every 3 months early in treatment, then annually for maintenance.
Feminizing Therapy Labs: $15-18 per draw
Frequent monitoring (every 3 months) → Estimated monthly cost: $5-$6 per month
Maintenance monitoring (once per year) → Estimated monthly cost: $1.50 per month
Masculinizing Therapy Labs: $12 per draw
Frequent monitoring (every 3 months) → Estimated monthly cost: $4 per month
Maintenance monitoring (once per year) → Estimated monthly cost: $1 per month
Get Started with Gender-Affirming Care Today
At PridePoint Health, we are proud to provide affirming, expert-led hormone therapy for transgender and gender diverse adults in Oregon and Washington. No matter where you are—whether in a city or a rural town—we are here to support you every step of the way.
📅 Schedule a consultation today and take the next step in your gender-affirming care journey.