Masculinizing Therapy: Timeline of Changes

Changes may vary in terms of onset and extent, generally occurring within months but reaching full effect over several years:

Effect Expected Onset Expected Maximum Effect
Increased libido 1-3 months Variable
Skin oiliness/acne 1-6 months 1-2 years
Cessation of menses 2-6 months Not applicable
Clitoral enlargement 3-6 months 1-2 years
Vaginal atrophy 3-6 months 1-2 years
Body fat redistribution 3-6 months 2-5 years
Facial/body hair growth 3-6 months 3-5 years
Voice deepening 3-12 months 1-2 years
Increased muscle mass/strength 6-12 months 2-5 years
Scalp hair loss >12 months Variable