Feminizing Therapy: Timeline of Changes

Changes may vary in terms of onset and extent, generally occurring within months but reaching full effect over several years:

Effect Expected Onset Expected Maximum Effect
Mood changes (irritable, angry) 1-3 months (typically mild) Variable
Decreased spontaneous erections 1-3 months 3-6 months
Decreased libido (sex drive) 1-3 months 1-2 years
Sexual dysfunction (absent erections, infertility) Variable Variable
Halting Scalp Hair Loss 1-3 months (minimal regrowth) 1-2 years
Softening of skin 3-6 months Variable
Decreased muscle mass/strength 3-6 months 1-2 years
Breast growth 3-6 months 2 years
Decreased testicular volume 3-6 months 2-3 years
Body fat redistribution 3-6 months 2-5 years
Decreased sperm production Variable Variable
Thinning and slowed growth of facial/body hair 6-12 months >3 years