Long-Acting Injectable PrEP With Apretude in Portland, Oregon

At PridePoint Health in Portland, Oregon, we are proud to offer Apretude® (cabotegravir)—the first long-acting injectable PrEP medication approved by the FDA. Apretude allows you to say goodbye to the daily pill routine and enjoy a more convenient, discreet, and reliable way to protect yourself from HIV. With just one injection every two months, Apretude provides highly effective HIV prevention that fits seamlessly into your lifestyle.

Live remote from our
Portland, OR clinic?

Black outline map of the state of Oregon and Washington with a gray star marking a location in Portland, Oregon

  • We welcome patients from across Washington and Oregon for injectable PrEP.

  • With appointments only every 2–6 months, many of our Yeztugo and Apretude patients travel from throughout the Pacific Northwest.

  • We offer flexible scheduling and coordinate all your labs and paperwork remotely—so your in-person visits are quick and stress-free.

Two men sitting at a meeting table, smiling, with a third person facing away from the camera. The man on the left has a mustache and is wearing a coral shirt, holding a pen and a document. The man in the middle has tattoos on his arm and is wearing a maroon shirt. The person on the right, partially visible, has short hair and is working on a laptop. A wall with colorful charts or diagrams is in the background.

Why Choose Apretude?

  • Convenience — No daily pills to remember.

  • Privacy — Administered privately at our Portland clinic.

  • Proven effectiveness — In two large clinical trials, Apretude reduced HIV risk by 66%–89% compared to daily Truvada®, largely due to improved adherence with injections.

  • FDA-Approved for Adolescents & Adults — Available for anyone age 12+ who weighs at least 35 kg (77 lb) and tests HIV-negative before starting.

  • Supportive Care — Guided by clinicians experienced in LGBTQ+ health and HIV prevention.

Personalized, Inclusive Care — Beyond the Basics

We go beyond simply prescribing PrEP. At PridePoint Health, you work directly with a physician who knows you, not an app or a rotating telehealth provider. We specialize in LGBTQ+ health and offer a full spectrum of options, including oral PrEP, long-acting injections like Apretude® and Yeztugo®, and tailored prevention strategies such as Doxy-PEP.

Unlike national mail-order services, we provide both virtual convenience and local, in-person care at our Portland clinic — including injectable PrEP administration, same-day or next-day STI evaluation and treatment, and optional discreet in-clinic dispensing. We integrate your PrEP plan with comprehensive sexual health services and evidence-based care that reflects your needs, values, and lifestyle.

A pridepoint doctor in a white coat sitting at a desk, smiling and talking with a patient in a red jacket, in a medical office setting.

Getting Apretude at PridePoint Health

At PridePoint Health, we make starting Apretude simple, discreet, and personalized—delivered by clinicians who understand LGBTQ+ health. Our goal is to make every step clear and hassle-free.

Here’s how it works:

  1. Check Your Insurance Coverage (Recommended)

    Before signing up, you can verify if your insurance covers Apretude using the VivviConnect program.

    • Choose “Online” on the VivviConnect site

    • Ensure you allow at least 1-2 communication options so ViiVConnect can follow up with you directly

    • Submit your enrollment and speak with an access coordinator to determine coverage

    For more details, see our Apretude Coverage & Cost Guide (PDF).

  2. Sign Up With PridePoint

    Once you’ve confirmed coverage—or if you’d like help navigating the process—sign up online. We have no sign-up fees and you can cancel anytime.

  3. Schedule a Visit

    Meet with your PridePoint clinician to discuss your goals, health history, and whether Apretude is right for you.

  4. Complete Initial Labs

    We’ll order HIV and STI screening, along with other labs needed to confirm you’re eligible and safe to start injectable PrEP.

  5. Start the Oral Lead-In

    Before receiving your first injection, you’ll take oral cabotegravir (the same medication in Apretude) once daily for 4 weeks. This helps confirm medication tolerance and safety.

  6. Receive Injections In-Clinic

    After completing the oral lead-in, your first injection is given in clinic. The second is scheduled 1 month later, then every 2 months ongoing.

  7. Ongoing Support & Follow-Up

    We handle any paperwork or refill logistics, coordinate regular lab monitoring, and are here between visits for urgent STI concerns or questions.

Want to know if your insurance covers Apretude?

Download our step-by-step guide to check coverage and explore cost-savings programs before your first visit.

💉 Apretude (Cabotegravir)
PrEP Dosing Schedule

Option 1: With Oral Lead-In (Optional) — Helps assess tolerance before injections.

  1. Oral Phase:

    • Take 1 tablet (30 mg) daily for 28 days

  2. First Injection:

    • Receive 1 injection (600 mg, intramuscular) on Day 29

  3. Second Injection:

    • Another 600 mg injection, 1 month after the first

  4. Ongoing Maintenance:

    • Injections continue every 2 months

Option 2: Direct-to-Injection (No Oral Lead-In) — For those ready to start right away.

  1. First Injection:

    • Receive 1 injection (600 mg, intramuscular)

  2. Second Injection:

    • Another 600 mg injection, 1 month later

  3. Ongoing Maintenance:

    • Injections continue every 2 months

Missed a Dose?

  • If it’s been more than 3 months since your last injection, a restart or temporary use of daily pills may be needed—check with your PridePoint clinician

Two men sitting on chairs in an office, engaged in conversation. One man is holding a bouquet of yellow flowers, and the other has a coffee cup. There is a large framed picture of a forest canopy on the wall behind them.

Take control of your health and experience the freedom of long-acting PrEP with Apretude.

Contact us to learn more or sign up today and ask about adding Apretude to your membership!

Looking for Twice-Yearly
Injectable PrEP?

In addition to Apretude every two months, PridePoint Health also offers Yeztugo® (lenacapavir)—a new, FDA-approved injectable PrEP option administered just twice per year. Learn more about Yeztugo here »